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Rekombinanter VEGF (Bevacizumab Biosimilar) Antikörper

Dieser Humanized Monoklonal Antikörper erkennt spezifisch VEGF (Bevacizumab Biosimilar) in FACS und in vivo. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7200653

Kurzübersicht für Rekombinanter VEGF (Bevacizumab Biosimilar) Antikörper (ABIN7200653)

Target

VEGF (Bevacizumab Biosimilar)

Antikörpertyp

Recombinant Antibody

Reaktivität

Human

Wirt

  • 2
  • 1
  • 1
  • 1
  • 1
Humanized

Klonalität

  • 3
  • 3
Monoklonal

Konjugat

  • 6
Dieser VEGF (Bevacizumab Biosimilar) Antikörper ist unkonjugiert

Applikation

  • 4
  • 3
  • 3
  • 3
  • 3
Flow Cytometry (FACS), In vivo Studies (in vivo)

Güteklasse

Research Grade
  • Verwendungszweck

    Bevacizumab Biosimilar, Human VEGF Monoclonal Antibody

    Spezifität

    The monoclonal antibody Bevacizumab biosimilar specifically binds to the human VEGF-A.

    Produktmerkmale

    Bevacizumab, the humanized anti-VEGF-A monoclonal antibody, produces angiogenesis inhibition and slows the growth of new blood vessels. As the first clinically available angiogenesis inhibitor in the United States, Bevacizumab is used for treatment of certain metastatic cancers, certain lung cancers, renal cancers, ovarian cancers, breast cancers, and glioblastoma multiforme of the brain. Vascular endothelial growth factor A (VEGF-A) stimulates angiogenesis in a variety of cancers, including colorectal, lung, breast, glioblastoma, kidney, and ovarian cancers.

    Aufreinigung

    Protein A or G affinity column

    Reinheit

    >95 % by reducing SDS-PAGE

    Sterilität

    0.2 μm filtered

    Endotoxin-Niveau

    < 1 EU per 1 mg of the protein by the LAL method

    Immunogen

    The monoclonal antibody Bevacizumab biosimilar was produced in the bevacizumab biosimilar CHO stable cell line.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by bevacizumab.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    > 3 mg/mL

    Buffer

    PBS, pH 7.4, no stabilizers or preservatives.

    Konservierungsmittel

    Without preservative

    Lagerung

    4°C,-20 °C

    Informationen zur Lagerung

    12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.

    Haltbarkeit

    12 months
  • Target

    VEGF (Bevacizumab Biosimilar)

    Andere Bezeichnung

    Bevacizumab Biosimilar

    Substanzklasse

    Biosimilar
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